TABLE 3

h-MAbs that cross-react with nontargeted pneumococcal serotypes

h-MAb target (bead region)Serotype(s) with which the h-MAb cross-reactsa
6A (13)6B,b 6C, 6D
6B (25)6A,b 6D
7F (42)7A
9N (34)9L, 18A, 43, 47A
9V (38)9A, 9L
10A (29)10B, 10C, 10F, 33C, 39
11A (57)11C, 11D, 11E, 16A, 16F, 18A, 18B, 18C, 45
12F (54)12B, 22A, 44
14 (43)9L, 9Nb
15B (61)15A, 15C, 15F, 11D, 12B, 18A
18C (27)18A, 18B, 18F, 35C, 42
19A (35)19F,b 9A, 9L, 9Vb
19F (59)19Ab
22F (26)22A, 43
23F (18)32A, 32F
33F (63)33A, 33B, 33D
  • a Serotypes in boldface indicate a cross-reaction with a different serogroup.

  • b Cross-reaction with a polysaccharide antigen detected in the 25-plex assay.