TABLE 1

Comparison of serum hemagglutination inhibition antibody responsesa

HAI assay target and time pointGMT (95% CI)P value
IIV (n = 18)LAIV (n = 18)
Influenza A/H1N1 virus
    Prevaccination11.76 (6.2, 22.4)11.11 (6.3, 19.9)0.89
    Postvaccination, day 747.03 (24.3, 91.1)9.33 (5.4, 16.3)<0.001
    Postvaccination, day 45101.59 (51.6, 200)12.70 (7.0, 23.2)<0.0001
Influenza A/H3N2 virus
    Prevaccination6.35 (4.1, 9.9)7.44 (4.6, 12.0)0.63
    Postvaccination, day 717.96 (10.5, 30.8)7.13 (4.1, 11.7)<0.02
    Postvaccination, day 4532.00 (17.5, 58.4)9.70 (5.9, 16.0)<0.01
Influenza B virus
    Prevaccination7.41 (5.2, 10.6)10.71 (6.6, 17.5)0.25
    Postvaccination, day 721.77 (14.2, 33.4)11.31 (6.8, 18.77)0.061
    Postvaccination, day 4540.32 (24.4, 66.7)12.70 (7.9, 20.5)<0.01
  • a The P values for comparisons of HAI GMT values among treatment groups were calculated by the t test. CI, confidence interval.