TABLE 1

M. paratuberculosis challenge strain fecal sheddinga

Vaccination groupFecal shedding (CFU/g) by month postchallenge (mean [range])
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PBS0 (0–0)0 (0–0)5 (0–10)7 (0–13)10 (0–20)0 (0–0)22 (13–30)55 (50–60)63 (33–127)116 (0–463)6 (0–13)22 (0–47)15 (0–60)
pgsH0 (0–0)0 (0–0)20 (0–40)9 (0–17)40 (0–80)0 (0–0)5 (0–10)5 (0–10)17 (0–40)0 (0–0)0 (0–0)0 (0–0)6 (0–37)
Mycopar7 (0–13)9 (0–17)0 (0–0)5 (0–10)5 (0–10)0 (0–0)19 (0–37)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)
pgsN0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)0 (0–0)
  • a A 3 CFU limit of detection was used. No M. paratuberculosis colonies were recovered from any of the goats in the naive group at any time point; hence, they are not represented here.