TABLE 1

Host and environmental risk factors for otitis-prone and healthy children assessed by a Ply neutralization assay and a MOPA

ParameterPly neutralization assayMOPA
Value for groupP valueValue for groupP value
Otitis prone (n = 165)Healthy (n = 61)Otitis prone (n = 20)Healthy (n = 20)
Mean age (mo) (range)21.2 (7.3–36.0)18.7 (7.3–35.0)0.0321.0 (10.9–33.5)18.3 (7.0–35.0)0.07
% male subjects62720.1565850.14
% of subjects at day care ≥4 h/wk62a32b<0.00150300.20
% of subjects fully PCV7 vaccinated99970.30100100
% of subjects taking antibiotics22c20b0.7700
% of subjects with no. of AOM episodes
    3–43355
    5–71810
    8–93525
    10+1510
% of subjects with pneumococcal carriage42260.0350350.34