TABLE 4

Protection against B. burgdorferi challenge by passive immunization with monoclonal antibodies

Antibody sourceNo. positive/total no.No. of mice positive/total no.% mice protected
SkinJointHeartBladderEarAll sites
Normal mouse serum3/33/33/33/33/315/153/30
1-5A100/50/50/50/50/50/250/5100
1-8B70/51/5a0/50/50/51/251/580
2-8C100/50/50/50/50/50/250/5100
2-2H85/53/35/55/55/523/235/50
Serum pool M-OspCB313/33/33/33/33/315/153/30
Serum pool D-OspCB311/51/51/51/51/55/251/580
  • a Culture did not grow out, but spirochetes were observed in one field on day 7 attached to a fragment of tissue debris.