TABLE 2

Total WBC, neutrophil, lymphocyte, and monocyte counts and neutrophil/lymphocyte ratios at baseline and for sham-treated rats, controls, and ALM-treated rats over 6 days^a

Rat group (n) and time point^b	Total WBC count (10⁹/liter)	Neutrophil count (10⁹/liter)	Lymphocyte count (10⁹/liter)	Monocyte count (10⁹/liter)	Neutrophil/lymphocyte ratio
Baseline (8)	9.07 ± 0.71	1.60 ± 0.19	7.21 ± 0.62	0.26 ± 0.05	0.2 ± 0.03
2 h
Sham (8)	7.41 ± 0.75	4.75 ± 0.51*	2.2 ± 0.36*	0.47 ± 0.09	2.4 ± 0.4*
Control (8)	8.56 ± 1.21	4.92 ± 1.09*	3.05 ± 0.51*	0.59 ± 0.14*	1.8 ± 0.4*
ALM (8)	7.8 ± 0.83	4.79 ± 0.59*	2.37 ± 0.25*	0.64 ± 0.12*	2.1 ± 0.2*
Day 1
Sham (8)	7.85 ± 0.5	4.82 ± 0.46*	2.6 ± 0.13*	0.43 ± 0.1	1.9 ± 0.2
Control (8)	4.82 ± 0.66^	3.11 ± 0.49^	1.5 ± 0.23+	0.21 ± 0.03^∼	2.1 ± 0.2^*
ALM (8)	6.96 ± 0.59*	4.8 ± 0.42*	1.8 ± 0.2*	0.37 ± 0.08	2.8 ± 0.3*
Day 2
Sham (8)	8.11 ± 0.92	4.41 ± 0.77*	3.35 ± 0.38*	0.35 ± 0.04	1.4 ± 0.4*
Control (2)	6.37 ± 0.04	3.40 ± 0.02	2.69 ± 0.07*	0.29 ± 0.02	1.3 ± 0.04*
ALM (7)	7.74 ± 0.61	4.27 ± 0.34*	3.13 ± 0.31*	0.33 ± 0.03	1.4 ± 0.1*
Day 4
Sham (8)	11.68 ± 0.98	6.87 ± 0.93*	4.24 ± 0.45*	0.57 ± 0.11	1.7 ± 0.3
Control (2)	12.22 ± 6.33	8.95 ± 5.34*	2.61 ± 0.72*	0.67 ± 0.28	3.1 ± 1.2*
ALM (7)	13.43 ± 1.23*	8.5 ± 1.12*	3.93 ± 0.64*	1.0 ± 0.16⁺	3.0 ± 1.0*
Day 6
Sham (8)	9.9 ± 1.54	5.95 ± 0.95*	3.23 ± 0.85*	0.72 ± 0.19*	2.8 ± 0.9*
Control (2)	9.88 ± 0.02	6.68 ± 0.12*	2.54 ± 0.2*	0.72 ± 0.02	2.7 ± 0.3
ALM (7)	9.14 ± 0.65	5.87 ± 0.5*	2.6 ± 0.65*	0.67 ± 0.13*	3.0 ± 0.6*
Death
CED (4)	2.91 ± 1.02*	1.69 ± 0.55	0.95 ± 0.41*	0.26 ± 0.1	2.2 ± 0.3*
CLD (2)	12.79 ± 8.42	9.15 ± 5.94*	2.92 ± 2.1*	0.68 ± 0.34*	3.5 ± 0.5*
ALM LD (1)	3.17	2.11	0.78	0.29	2.7

↵a Values are for survivors through day 6, followed by animals with early and late death. *, P < 0.05 versus value at baseline; ^, P < 0.05 versus values for all groups; ∼, P < 0.05 versus value for sham; ⁺, P < 0.05 versus values for sham and baseline. CED, control early death; CLD, control late death; LD, late death.
↵b n = number of animals.