TABLE 1

Borrelia strains used in this study

StrainDescriptionAntibiotic resistanceReference
B. burgdorferi B31-A3Wild-type, infectious clone of North American tick isolate B31, missing cp9None49
B. burgdorferi B31-A3 Δp66 mutantDeletion of p66 in B31-A3; noninfectiousKanamycin31
B. burgdorferi B31-A3 p66cpComplement of Δp66 on shuttle vector pBSV2G; overproduces P66, noninfectiousKanamycin, gentamicin31
B. burgdorferi N40 D10/E9Wild-type, infectious clone of North American tick isolate N40None50
B. garinii PBrWild-type, infectious human CSF isolate from GermanyNone37