TABLE 3

Association between presence of IgG antibodies at 12 months of age and first occurrence of a malaria infection after 12 months of age

Assay/antigen testedNo. testedNo. of malaria eventsHazard ratio (95% confidence interval)P
Serology
    LSA167171.84 (0.71–4.77)0.21
    CSP67172.64 (1.00–6.97)0.05
    PfCelTOS67172.67 (0.94–7.61)0.07
    SE5067174.51 (1.46–13.9)0.009
    SE3667172.35 (0.89–6.19)0.08
    MSP142 (3D7)67171.90 (0.73–4.99)0.19
    MSP142 (FVO)67174.37 (1.52–12.6)0.006
    MSP142 (FUP)67173.13 (1.14–8.57)0.03
    EBA14067173.27 (1.19–8.95)0.02
    EBA17567173.12 (1.18–8.25)0.02
    EBA18167171.76 (0.68–4.56)0.25
    AMA1 (3D7)67172.98 (1.07–8.33)0.04
    AMA1 (FVO)67176.21 (1.67–23.1)0.006
Variant surface antigen assay
    BFD 200667172.43 (0.78–7.56)0.13
    Msambweni 200667171.00 (0.13–7.60)1.00
    3D767172.45 (0.56–10.8)0.23
Growth and invasion inhibition assay
    Sial Dep IIA65171.64 (0.60–4.47)0.34
    W2mef GIA65171.52 (0.49–4.74)0.47
    MSP1-19 IIA65171.56 (0.36–6.84)0.55
    D10 GIA65171.49 (0.20–11.3)0.70