Participant detailsa

CharacteristicValue for clinical group:
ControlCerebral malariaSevere malarial anemiaUncomplicated malaria
No. of patients
    Died during admission410
    Followed up in convalescence182134
Sex (male/female ratio)29:1310:1919:1138:16
Median age, mo (range)20 (5–76)30 (5–84)23 (5–38)27 (6–58)
Median no. of parasites/μl blood (range)041,800 (900–517,000)3,500 (20–296,000)52,300 (460–768,000)
Median Blantyre coma score (range)51 (0–2)55
Median hemoglobin, g/dl (range)11.2 (7.0–14.1)7.7 (5.3–12.5)3.9 (2.4–4.9)9.3 (5.1–13.0)
  • a Subjects were children with cerebral malaria, severe malarial anemia, or uncomplicated malaria presenting to the Pediatric Accident and Emergency Clinic at Queen Elizabeth Central Hospital in Blantyre, Malawi. Control subjects were children admitted for elective surgical procedures who were medically well.