TABLE 3

Characteristics of the cohort of 160 women with high-grade CIN enrolled in a natural history study (33) and treated at Johns Hopkins University, Baltimore, MD, USA

DiagnosisaNo. (%) of patients
    HGSIL132 (82.5)
    Benign/CCSM11 (6.9)
    ASCUS2 (1.3)
    ASC-H2 (1.3)
    AIM1 (0.6)
    LSIL-H1 (0.6)
    LSIL11 (6.9)
HPV16 status (HGSILs only)
    HPV16+87 (54.4)
    HPV1642 (26.3)
    Not done3 (1.9)
HPV16 status (all patients)
    HPV16+99 (61.9)
    HPV1653 (33.1)
    Not done7 (4.4)
    Indeterminate1 (0.6)
Race/ethnicity
    White109 (68.1)
    Black37 (23.1)
    Asian5 (3.1)
    Hispanic9 (5.6)
Age group (yr)
    18–2016 (10.0)
    21–3086 (53.8)
    31–4039 (24.4)
    41–5013 (8.1)
    ≥506 (3.8)
  • a Serum samples were collected at the screening visit and at subsequent treatment and follow-up visits when available. HGSIL, high-grade squamous intraepithelial lesion; CCSM, cervical cancer-specific mortality; ASC-H, high-grade atypical squamous cells; AIM, atypical immature squamous metaplasia; LSIL-H; high-grade squamous intraepithelial lesion; LSIL, low-grade squamous intraepithelial lesion.