TABLE 2

Commercially available CMV IgG avidity kitsa

Manufacturer (test name)MethodDissociating agentLow-avidity scorebHigh-avidity scorebCan be purchased in USA?
Bio-RadELISAUrea<40>55No
DiesseELISAUrea<30>40Yes
EuroimmunELISAUrea<40>60Yes
RadimELISAUrea<35>45Yes
TechnogeneticsELISAPotassium thiocyanate<25>45No
VidiaELISAUrea<40>60Yes
Virion/SerionELISAUrea<45>55Yes
MikrogenIBLUreaNANAYes
bioMérieux (Vidas)ELFAUrea<40>65No
DiaSorin (Liaison)CIAUrea<20>30No
Roche (Elecsys)V-CIAGuanidine chloride<45>55No
Abbott (Architect)CMIANonec<50>60No
  • a Abbreviations: ELISA, enzyme-linked immunosorbent assay; IBL, immunoblotting; ELFA, enzyme-linked fluorescence assay; CIA, chemiluminescent immunoassay; V-CIA, voltage-induced chemiluminescent assay; CMIA, chemiluminescent microparticle immunoassay; NA, not applicable.

  • b Avidity index values are formatted as percentages for consistency.

  • c The assay utilizes CMV soluble antigen that blocks attachment of high-avidity IgG to CMV-coated microparticles.