Serogroup | Study group | Prevaccination hSBA GMT (95% CI) | Day 7 hSBA GMT (95% CI) | Day 28 hSBA GMT (95% CI) |
---|---|---|---|---|

A | MenACWY-CRM | 3.2 (2.6, 4.0) [n = 75] | 4.3 (3.2, 5.7) [n = 72] | 16.7 (10.9, 26.1) [n = 71] |

MenACWY-PS | 3.9 (3.0, 5.1) [n = 75] | 5.9 (4.2, 8.3) [n = 73] | 26.5 (16.1, 43.5) [n = 75] | |

C | MenACWY-CRM | 6.3 (4.6, 8.5) [n = 73] | 14.3 (9.7, 21.3) [n = 71] | 32.7 (20.1, 53.2) [n = 68] |

MenACWY-PS | 11.1 (8.2, 15.0) [n = 75] | 27.0 (18.8, 38.6) [n = 74] | 98.9 (64.9, 150.6) [n = 75] | |

W | MenACWY-CRM | 12.0 (8.0, 18.0) [n = 75] | 20.67 (13.4, 31.8) [n = 68] | 64.1 (40.7, 100.8) [n = 66] |

MenACWY-PS | 26.2 (17.5, 39.3) [n = 74] | 34.5 (23.4, 50.7) [n = 73] | 53.1 (35.6, 79.0) [n = 74] | |

Y | MenACWY-CRM | 3.8 (3.0, 4.7) [n = 75] | 5.5 (4.1, 7.5) [n = 70] | 15.4 (10.1, 23.5) [n = 71] |

MenACWY-PS | 5.6 (4.2, 7.5) [n = 75] | 9.8 (7.1, 13.7) [n = 74] | 21.7 (13.9, 33.8) [n = 75] |

↵a Abbreviations: hSBA, human complement source serum bactericidal activity; GMT, geometric mean titers; CI, confidence intervals. 95% confidence intervals are shown in parentheses, and numbers of samples are shown in square brackets. The numbers of samples at each time point differed due to missed visits, participant dropout, insufficient serum for assays, or failed assays.