TABLE 1

Cytokine production by splenocytes of immunized Kunming mice after stimulation with Toxoplasma lysate antigena

Mouse groupCytokine production (mean ± SD) (pg/ml)
IFN-γIL-2IL-4IL-10IL-12(p70)
pVAX-CDPK3982.68 ± 378.22b266.04 ± 9.13b<15136.53 ± 71.63b96.84 ± 4.06b
pVAX I34.91 ± 11.23<15<15322.50 ± 179.1715.14 ± 7.63
PBS36.34 ± 4.83<15<15356.13 ± 175.2722.31 ± 4.40
Blank control47.28 ± 16.60<15<15477.25 ± 87.5325.29 ± 17.35
  • a Splenocytes from mice were harvested 2 weeks after the final immunization.

  • b Statistically significant difference (P < 0.05).