TABLE 2

Fecal concentrations of IL-13, IL-8, IL-23, TNF-α, IFN-γ, lactoferrin, and calprotectin from the CDI-positive and CDI-negative diarrheal stools and nondiarrheal stools evaluateda

Patient groupConcn (pg/ml)Concn (μg/ml)
IL-13IL-8IL-23TNF-αIFN-γLactoferrinCalprotectin
CDI positive (n = 50)
    Mean323.8318.272259.869.743.423.8
    Median277.4242390.533.75831.418
    Range35.7–1,15013.1–1,529110.0–7,0692.7–163.68.7–225.73.0–155.22.8–70.2
    P value0.010.0220.0010.0780.0670.0190.029
CDI negative (n = 50)
    Mean141.184.7946.731.248.324.88.8
    Median138.883.3932.625.731.56.36.5
    Range14.3–319.38.5–191.6185.5–2,0160.6–177.70.04–204.30.6–140.32.0–31.0
    P value0.0240.0340.00320.0550.0880.0280.054
Nondiarrheal control (n = 45)
    Mean234.379.81,61722.357.66.810.2
    Median203.5527681850.25.68.7
    Range19.2–701.721.4–295.7489.0–6,8100.3–83.310.9–143.30.5–35.01.8–33.2
    P value0.060.010.0410.0920.0020.0690.073
  • a Concentrations were determined by quantitative ELISA (R&D Systems, Minneapolis, MN).