Table 1

Vaccine groupsa

Group no.Vaccine
1Chitosan-pcDNA3.1 (mock)
2Chitosan-pVP1
3Chitosan-pHMGB1
4Chitosan-pVP1 plus chitosan-pHMGB1
  • a The mice in each group were immunized 4 times biweekly at a dose of 50 μg of each plasmid. The mice that received pVP1 alone, pHMGB1, or empty plasmid also received an additional 50 μg pcDNA3.1 so that the total DNA amount was 100 μg.