Table 2

Comparison of BioPlex 2200 Syphilis IgM to IgM WB

Assay and resultIgM WB result (no. of samples)% sensitivity (95% CI)% specificity (95% CI)% agreement (95% CI)κ value
PositiveNegative
BioPlex 2200 Syphilis IgMa
    Positive28584.8 (68.1–94.9)94.9 (93.1–96.3)94.5 (92.9–96.1)0.53
    Negative40747
BioPlex 2200 Syphilis IgMb
    Positive28584.8 (68.1–94.9)91.0 (81.5–96.6)89.0 (86.6–91.2)0.75
    Negative661
  • a Data represent total results, considering all the 820 sera.

  • b Data represent results obtained when sera obtained from untreated syphilis patients were studied.