Table 2

B. burgdorferi tissue loads measured by qPCRa

ParameterSpleenHeartJoint
AdjRevARevA + AdjAdjRevARevA + AdjAdjRevARevA + Adj
Copy no.bND4 × 10−6 ± 1 × 10−62.5 × 10−73 × 10−11 ± 2 × 10−1110 × 10−11 ± 3 × 10−115 ×10−11 ± 2 × 10−11ND1 × 10−5 ± 7 × 10−114 × 10−5 ± 3 × 10−12
No. of positive samples/no. of tissues sampled0/84/81/84/84/87/80/83/83/8
  • a For each tissue type, the value is shown for mice treated with adjuvant only (Adj), RevA alone, and RevA plus Adj. ND, not detected.

  • b Average B. burgdorferi copy number per pg of mouse DNA ± standard error of the mean for B. burgdorferi-positive specimens only.