Table 2

P values and parameter estimates with the full zero-inflated model (IFN-γ)

AntigenP value for the indicated group vs the controlVaccination response at three vaccinationsP value for:
Vac2wVac8wVac16wEqual?P valueVaccination at all time points vs the controlEffect of age
MAP02170.130.180.006**Yes0.280.04*0.64
MAP1609c0.300.003**0.005**Yes0.150.005**0.68
MAP15080.0009***0.02*<0.0001***Yes0.55<0.0001***0.08
MAP3701c<0.0001***a<0.0001***a<0.0001***aYes0.70a<0.0001***NA
MAP3783<0.0001***a<0.0001***a<0.0001***aNo0.02aNAb0.13a
  • a All noncontrols were positive. For group Vac2w and Vac16w (MAP3783), the difference is significant with respect to the level of response (P = 0.03 and 0.01). For MAP3701c, all controls except three were positive, one at vaccination number 2 and two at vaccination number 3. For MAP3701c, the P value on time for the positive level is thus based on a very small sample, which makes it unreliable. *, P < 0.05; **, P < 0.01; ***, P < 0.001.

  • b NA, not applicable.