Table 1

Demographic and clinical characteristics

VariableValue for groupP valuea
Chronic HCV, no cirrhosis (n = 35)Chronic HCV, cirrhosis (n = 40)Alcohol/NASH cirrhosis (n = 21)Uninfected, no cirrhosis (n = 22)
Age, yr (mean ± SD)57.0 ± 8.860.8 ± 4.760.0 ± 6.258.4 ± 7.60.06c
Gender, no. (%)
    Female2 (5.7)1 (2.5)0 (0.0)1 (4.5)0.76b
    Male33 (94.3)39 (97.5)21 (100.0)21 (95.5)
Ethnicity, no. (%)
    Caucasian19 (54.3)26 (65.0)17 (81.0)15 (68.2)0.49
    Black10 (28.6)8 (20.0)1 (4.8)4 (18.2)
    Other6 (17.1)6 (15.0)3 (14.3)3 (13.6)
Hepatocellular carcinoma, no. (%)
    Yes0 (0.0)7 (17.9)3 (14.3)0 (0.0)0.006b
    No35 (100.0)32 (82.1)18 (85.7)22 (100.0)
BMI (mean ± SD)27.2 ± 4.628.4 ± 4.3629.2 ± 6.329.3+-5.20.40c
Alcohol, no. (%)
    Yes2 (5.9)16 (41.0)17 (81.0)5 (22.7)<0.0001
    No32 (94.1)23 (59.0)4 (19.0)17 (77.3)
ATP (ng/ml), median (IQR)432 (366.2–552.1)256.7 (176.5–425.5)392.1 (280.3–519.4)456.3 (301.6–726.8)0.0001c
ALT (U/liter), median (IQR)40 (26–64)67 (39–96.5)23 (15–35)27 (20–52)<0.0001c
  • a P values were calculated from the chi-square test for category variables and ANOVA for continuous variables unless otherwise indicated.

  • b P values were calculated from Fisher's exact test.

  • c The variable was rank transformed.