Table 5

Serum antibody responses to O78 LPS

GroupNo. (%) of positive responsesa
Day 7 postchallengeDay 28 postchallenge
Serum IgGSerum IgASerum IgGSerum IgA
ACE527 (n = 29)2 (6.9)23 (79.3)7 (24.1)22 (75.9)
Placebo (n = 27)8 (29.6)24 (88.9)13 (48.1)22 (81.5)
  • a Positive responses are defined as a 2.5-fold increase over baseline titer.