Serum antibody responses to O78 LPS
| Group | No. (%) of positive responsesa | |||
|---|---|---|---|---|
| Day 7 postchallenge | Day 28 postchallenge | |||
| Serum IgG | Serum IgA | Serum IgG | Serum IgA | |
| ACE527 (n = 29) | 2 (6.9) | 23 (79.3) | 7 (24.1) | 22 (75.9) |
| Placebo (n = 27) | 8 (29.6) | 24 (88.9) | 13 (48.1) | 22 (81.5) |
↵a Positive responses are defined as a 2.5-fold increase over baseline titer.