Table 2

Cytokine production by splenocytes of immunized Kunming mice after stimulation by STAga

GroupCytokine production (pg/ml)b
IFN-γIL-2IL-4IL-10
pVAX-ROP13 + pVAX/IL-181,107.28 ± 26.74A934.52 ± 13.03A257.54 ± 4.17A246.02 ± 10.61A
pVAX-ROP13826.75 ± 18.91B793.07 ± 22.09B163.23 ± 6.05B160.49 ± 3.14B
pVAX/IL-18671.39 ± 30.82C367.26 ± 21.89C71.62 ± 9.81C34.59 ± 11.46C
pVAX I52.33 ± 13.14D48.67 ± 8.32D52.00 ± 19.48C53.64 ± 9.25C
PBS47.63 ± 4.34D46.33 ± 10.04D50.72 ± 5.73C51.13 ± 3.93C
  • a Splenocytes from mice were harvested 2 weeks after the final immunization.

  • b Values for IFN-γ are for 96 h, values for IL-2 and IL-4 are for 24 h, and values for IL-10 are for 72 h. Values followed by the same letter showed no significant difference (P > 0.05), whereas different letters indicate significant differences (P < 0.05) in the same column.