Table 3

IgA BM responses to S. Typhi, S. Paratyphi A, and S. Paratyphi B

AntigenSerovarPeak % increasea (mean ± SE)P value compared to:Hierarchy of response
S. TyphiS. Paratyphi A
LPSS. Typhi0.15 ± 0.06S. Typhi > S. Paratyphi B = S. Paratyphi A
S. Paratyphi A0.053 ± 0.020.002
S. Paratyphi B0.064 ± 0.0190.0380.556
OMPS. Typhi0.234 ± 0.047S. Typhi ≥ S. Paratyphi B ≥ S. Paratyphi A
S. Paratyphi A0.135 ± 0.0460.039
S. Paratyphi B0.201 ± 0.0540.410.19
  • a Peak postvaccination increase in percentage of specific BM/total IgA SFC at day 42, 84, or 118 minus the corresponding prevaccination level.