Table 4

Overlapping MHC class I and II T cell epitopes

ProteinMHC class II T cell epitopeMHC class I T cell epitope
SequenceaPositionsSequencePositions
MAP1297ALYAGRFTLPQALAA226–240ALYAGRFTL226–234
MAP3393cLPGMVASATPLPVIG75–89GMVASATPL77–85
MAP3567KYNIHANAIAPIAAT184–198KYNIHANAI184–192
MAP3651cDQKRAYLPRMASGEI123–137LPRMASGEI129–137
MAP3523cHPMRFYNALGAIRAV393–407HPMRFYNAL393–401
MAP1168cSELSAAPSFPVRVPG139–153SELSAAPSF139–147
AAPSFPVRV143–151
MAP0187cWDYAALEPHISGQIN11–25DYAALEPHI12–20
LEPHISGQI16–24
MAP2487cYASSFEGPLPMPPSK14–28YASSFEGPL14–22
SSFEGPLPM16–24
EETGIKPPWAAEAFA107–121KPPWAAEAF112–120
PPWAAEAFA113–121
  • a The underlined residues are the 9-mer MHC class I T cell epitopes overlapping the 15-mer MHC class II T cell epitopes, offset at either the N-terminal or C-terminal end.