Table 3

High-affinity (IC50 of <50 nM) MHC class I and II T cell epitopes

ProteinEpitope sequence (positions)
Proteins with MHC class I T cell epitopes (9–mer)
    MAP2698cRPVANALTL (4–12)
HRELVEHFI (83–91)
IALRNYLVV (112–120)
LEEPILSGL (173–181)
EEPILSGLV (174–182)
HELFFSNLV (192–200)
LEYTRDETI (204–212)
TENDLRQVI (246–254)
DEPALKPFV (265–273)
    MAP3567RAVANYDSV (65–73)
VGLINSLAL (172–180)
KYNIHANAI (184–192)
NPNSASVFV (230–238)
    MAP3651cSPVSMPCYV (81–89)
VSMPCYVRV (83–91)
CYVRVTEQL (87–95)
IEQMKRIGI (61–69)
SNARRSGLI (178–186)
MEAGMAKLF (336–344)
    MAP3523cNATTNCFPM (115–123)
AYAQADNEI (247–255)
SEFDSNQQI (331–339)
    MAP2312cYGFMNEYPV (349–357)
SYQAISFKI (285–293)
NEEQKRKWL (108–116)
KEAAIAKMI (322–330)
NEYPVARHY (353–361)
MHC class II T cell epitopes (15–mer)
    MAP1168cTPIPVYVAAMGPKAL (155–169)
PIPVYVAAMGPKALQ (156–170)
IPVYVAAMGPKALQV (157–171)
PVYVAAMGPKALQVT (158–172)