Table 1

Age and sex distribution by vaccine response measure (IgG and SBA) for the initial and replication studies

Study and groupaNo. of participantsMean age (yr)No. (%) of males
Initial genetic study
    IgG responders47215.30267 (56.60)
    IgG nonresponders42514.40219 (51.50)
    rSBA responders72814.9076 (53.90)
    rSBA nonresponders14114.30397 (54.50)
Replication study
    School-aged children
        IgG responders711.603 (42.90)
        IgG nonresponders1489.1083 (56.10)
        rSBA responders379.8018 (48.60)
        rSBA nonresponders1189.0068 (57.60)
    Infants
        hSBA responders171.0543 (43.00)
        hSBA nonresponders1791.0553 (55.00)
  • a IgG responders were participants with IgG concentrations of ≥2 μg/ml, and nonresponders were participants with IgG concentrations of <2 μg/ml. rSBA responders were participants with rSBA response levels of ≥1:8, and nonresponders were participants with rSBA response levels of <1:8. hSBA responders were participants with hSBA response levels of ≥1:4, and nonresponders were subjects with hSBA response levels of <1:4.