Table 1.

Specificity and sensitivity of the MAb-based serotyping assay

MAb no.MAb designationSerotype specificityaIC50 (ng/ml)b
1Hyp1G418
2Hyp2M2210
3Hyp3M636
4Hyp4M346
5Hyp5M3512
6Hyp6AM36A3
7Hyp6BM16B77
8Hyp6DM56C/6D14
9Hyp7FM157F/7A52
10Hyp8M2810
11Hyp9NM39N8
12Hyp9VM79V/9A1
13Hyp10AG310A/3958
14Hyp11AM211A/11D/11F13
15Hyp11AM111E/(11A/11D/11F)15
16Hyp12FM312F26
17Hyp14M11145
18Hyp15BG515B/(15C)68
19Hyp17FM617F/17A6
20Hyp18CM118C5
21Hyp19AG119A5
22Hyp19FM319F5
23Hyp20G52029
24Hyp22FM222F/22A4
25Hyp23FG323F16
26Hyp33FG133F/33A18
  • a Serotypes in parentheses are those with partial cross-reaction. Hyp10AG3 does not cross-react with 10B, unlike Danish factor serum 10d (12).

  • b The PS concentration required to inhibit 50% of MAb binding to the enzyme-linked immunosorbent assay plate.