Table 1.

Anti-Intcv IgA concentrations and recovery of C. rodentium in feces from C57BL/6 mice immunized by the s.l. routei

ImmunizationIgA (ng/ml) before challenge12 hDay 4Day 10
IgA (ng/ml)CFU/g of feces (log10)IgA (ng/ml)CFU/g of feces (log10)IgA (ng/ml)CFU/g of feces (log10)
Saline8 ± 1115 ± 175.33 ± 0.421 ± 139.18 ± 0.32111 ± 696.69 ± 0.37
L. casei10 ± 814 ± 135.78 ± 0.716 ± 188.82 ± 0.726 ± 406.2 ± 0.83
L. casei-Intcv101 ± 55a,e132 ± 29a,f4.72 ± 0.63g70 ± 22b,h7.7 ± 0.6c24 ± 28b5.6 ± 0.59d
  • a,b,c,d Significantly different from saline (P = 0.02, P = 0.03, P = 0.001, and P = 0.01, respectively).

  • e,f,g,h Significantly different from L. casei; (P = 0.01, P = 0.02, P = 0.05, and P = 0.03, respectively).

  • i Statistical analyses were performed by the Mann-Whitney U test.