TABLE 4.

Evaluation of antibody profiles obtained by the methods compared

Test system and type of infectionNo. of samples with the following result by reference method:Sensitivity (%)aSpecificity (%)a
PrimaryPastNegative
IF92.790.7
    Primary7640
    Past3220
    Negative3017
CLIA-L93.894.6
    Primary7520
    Past5201
    Negative0113
    Unresolvedb133
CLIA-I89.097.7
    Primary7310
    Past8251
    Negative1016
ELISAc89.695.2
    Primary6920
    Past5230
    Negative3017
  • a Sensitivity and specificity for identification of recent infection.

  • b Unresolved samples were excluded from the calculations.

  • c For ELISA, data are results for 119 samples (77 primary infections, 25 past infections, and 17 negative result) determined by reference methods.