TABLE 3.

Evaluation of assays for detection of IgG against EBNAa

Assay and resultNo. of samples with the following ACIF result:Sensitivity (%)Specificity (%)Correlation (%)
PositiveNegative
IF, IgG EBNA-178.191.488.0
    Positive252
    Indeterminate16
    Negative685
CLIA-L, IgG EBNA-190.632.347.2
    Positive2928
    Indeterminate335
    Negative030
CLIA-I, IgG p7293.879.683.2
    Positive3015
    Indeterminate14
    Negative174
ELISA, IgG EBNA-1b87.589.989.3
    Positive287
    Indeterminate12
    Negative380
  • a For calculating sensitivity and specificity, indeterminate results were considered the most adverse.

  • b For ELISA, data are for 121 results (32 ACIF positive and 89 ACIF negative).