TABLE 2.

Evaluation of assays for detection of IgG against EBVa

Assay and resultNo. of samples with the following IIF result:Sensitivity (%)Specificity (%)Correlation (%)
PositiveNegative
IF, IgG p1879.494.481.6
    Positive850
    Indeterminate151
    Negative717
CLIA-L, IgG p1886.994.488.0
    Positive931
    Indeterminate00
    Negative1417
CLIA-I, IgG gp12594.410095.2
    Positive1010
    Indeterminate20
    Negative418
ELISA, IgG p18b89.110090.8
    Positive900
    Indeterminate30
    Negative818
  • a For calculating sensitivity and specificity, indeterminate results were considered the most adverse.

  • b For ELISA, data are for 119 results (101 IIF positive and 18 IIF negative).