Table 1.

Percentages of NK cells degranulating in response to the given stimuli, in relation to all NK cells

GroupnMedian % NK cells degranulating (10th to 90th percentiles)a
No stimuliK562PMA+IONPMA+ION+CB
Healthy donors400.4 (0.1–0.8)11.2 (5.1–21.8)11.8 (5.2–23.9)66.8 (32.5–88.5)
FRH, recurrence330.5 (0.1–1.2)7.7 (3.0–15.7)*4.3 (1.3–12.5)***49.4 (16.9–68.0)**
FRH, remission240.3 (0.1–0.7)8.2 (4.8–14.5)*5.5 (1.7–11.0)***39.1 (25.4–68.6)**
  • a *, P < 0.05; **, P < 0.01; ***, P < 0.001 (compared to the response to the same stimulus in healthy donors [Mann-Whitney U-test]).