Table 2.

Percentages of tissue occupied by different cell subtypes, surface antigens, and cytokines, with calculated statistical significance (P values), for specimens from CD and non-CD patientsa

Cell subtype, antigen, or cytokine% of tissue occupiedP value for inflamed CD vs noninflamed CD tissueP value for inflamed CD vs non-CD tissueP value for noninflamed CD vs non-CD tissue
Inflamed CD tissueNoninflamed CD tissueNon-CD tissue
B cells0.53940.66310.41920.7140.0660.097
Macrophages1.01640.63440.3830.6480.0410.086
Monocytes0.7150.660.6270.5070.5230.961
Neutrophils0.81191.312.4410.690.7310.396
CD80.57060.6950.2360.680.0670.091
CD40.57060.99330.75020.0140.8990.223
TNF-α0.41750.34810.120.2080.0490.023
IL-120.35810.39690.1960.3680.0030.017
  • a P values of <0.05 were considered significant and are shown in bold.