Table 1.

Sensitivity and specificity of IgG against single antigens or combinations of two antigensa

Antigen(s)% sensitivity% specificity
PTB(+) (n = 50)PTB(−) (n = 101)EPTB (n = 88)Total TB (n = 239)PD (n = 49)TST+ controls (n = 50)TST controls (n = 151)
38kDa76.0 (38/50)37.6 (38/101)20.5 (18/88)39.3 (94/239)89.8 (44/49)82.0 (41/50)90.1 (136/151)
38E680.0 (40/50)44.6 (45/101)28.4 (25/88)46.0 (110/239)93.9 (46/49)84.0 (42/50)89.4 (135/151)
AH62.0 (31/50)30.7 (31/101)26.1 (23/88)35.6 (85/239)91.8 (45/49)20.0 (10/50) D90.7 (137/151)
Rv361868.0 (34/50)47.5 (48/101)48.9 (43/88) D52.3 (125/239) D75.5 (36/49) A34.0 (17/50) D90.1 (136/151)
Rv3621c48.0 (24/50) D29.7 (30/101)22.7 (20/88)31.0 (74/239)85.7 (42/49)60.0 (30/50) A88.1 (133/151)
38kDa+38E684.0 (42/50)48.5 (49/101)30.7 (27/88)49.4 (118/239) B87.8 (43/49)80.0 (40/50)88.1 (133/151)
38kDa+AH90.0 (45/50) F52.5 (53/101) BF37.5 (33/88) B54.8 (131/239) EF83.7 (41/49)16.0 (8/50) E81.5 (123/151) BC
38kDa+Rv3621c86.0 (43/50) F51.5 (52/101) BF33.0 (29/88)51.9 (124/239) EF75.6 (39/49)54.0 (27/50) E80.8 (122/151) B
38kDa+Rv361892.0 (46/50) BF64.4 (65/101) CE52.3 (46/88) E65.7 (157/239) EF67.3 (33/49) E26.0 (13/50) E82.1 (124/151) BC
38E6+AH90.0 (45/50) F55.4 (56/101) F43.2 (38/88) BC58.2 (139/239) EF85.7 (42/49)20.0 (10/50) E80.8 (122/151) BC
38E6+Rv3621c90.0 (45/50) F55.4 (56/101) F37.5 (33/88) C56.1 (134/239) BF75.6 (39/49) B50.0 (25/50) E81.5 (123/151)
38E6+Rv361896.0 (48/50) BF69.3 (70/101) EF58.0 (51/88) E70.7 (169/239) EF73.5 (36/49) E30.0 (15/50) E81.5 (123/151) C
AH+Rv3621c72.0 (36/50) C46.5 (47/101) C35.3 (31/88)47.7 (114/239) EF83.7 (41/49)16.0 (8/50) F80.1 (121/151) B
AH+Rv361872.0 (36/50)53.5 (54/101) E55.7 (49/88) E58.2 (139/239) E71.4 (35/49) E18.0 (9/50)83.4 (126/151)
Rv3621c+Rv361872.0 (36/50) B59.4 (60/101) E52.3 (46/88) E59.4 (142/239) E69.4 (34/49)28.0 (14/50) B81.5 (123/151) C
  • a A, compared with 38kDa; B, compared with the first component of a combination; C, compared with the second component of a combination; D, compared with 38kDa; E, compared with the first component of a combination; F, compared with the second component of a combination. A, B, C, P < 0.05; D, E, F, P < 0.01.