TABLE 2.

Biological results for 3 cystic fibrosis patients with Aspergillus rhinosinusitis and bronchitisg

Patient no.Age (yr)GenderaAspergillosis diagnosisSerum sample no.Antibodies to A. fumigatusTotal IgEe (kIU/liter)No. of Aspergillus colonies in sputum
rAspf4c (kAU/liter)rAspf6c (kAU/liter)IgGb indexIE (precipitin no., enzymatic activitiesd)
186MBronchitis74<0.10<0.102.195, cat+48ND
75<0.10<0.101.786, cat+443
76<0.10<0.100.38026ND
77<0.10<0.102.334, cat+942
78<0.10<0.102.26NDf1
1923FBronchitis790.551.330.2519612
800.862.332.5832005
810.351.033.41312412
820.321.062.294, cat+1158
830.190.870.9910, cat+10141
2018FColonization84<0.10<0.100.9161628
85<0.10<0.100.867, cat+2985
Sinusitis86<0.10<0.101.367, cat+, chym+ND40
87<0.10<0.103.245, cat+ND20
88<0.10<0.101.355ND3
  • a M, male; F, female.

  • b Anti-Aspergillus ELISA IgG. An index value of >0.75 was considered positive.

  • c Specific IgE against two A. fumigatus recombinants measured by the Pharmacia UniCAP method. A result of >0.1 kAU/liter was considered positive.

  • d IE for precipitin detection. More than 2 precipitin lines was considered positive. Positive enzymatic activities (catalase and chymotrypsin) are indicated (+).

  • e Total IgE measured by the Pharmacia UniCAP method. A result of >500 kIU/liter was considered positive.

  • f ND, not determined.

  • g Positive results are shown in boldface type.