TABLE 1.

Summary of results comparing each immunoblot and Western blot assay with the FTA-ABS/TP-PA and RPR results

Test and resultNo. of samples
FTA-ABS/TP-PAaRPRb negative
PositiveNegative
ViraBlot assayc
    Positive6321
    Negative37457
Virotech immunoblotd
    Positive5710
    Negative67358
    Equivocal320
Marblot strip assaye
    Positive5500
    Negative16752
    Equivocal1096
  • a FTA-ABS and TP-PA resolved results.

  • b Samples originally subjected to the RPR only.

  • c The Treponema ViraBlot test kit IgG had overall agreement, sensitivity, and specificity values of 97.0%, 95.5% (95% CI, 90.4 to 97.9), and 97.8% (95% CI, 95.2 to 99.0%), respectively.

  • d The T. pallidum IgG line immunoblot had overall agreement, sensitivity, and specificity values of 96.4%, 90.0% (95% CI, 84.7 to 91.4%), and 99.2% (95% CI, 96.8 to 99.9%), respectively.

  • e The T. pallidum IgG Marblot strip test system had overall agreement, sensitivity, and specificity values of 99.4%, 98.2% (95% CI, 94.3 to 98.2%), and 100.0% (95% CI, 98.2 to 100.0%), respectively.