TABLE 1.

Protective efficacy of the SV and EV76 against a lethal subcutaneous challenge in female mice

Treatment groupaChallenge time (days postimmunization)Survival (no. of survivors/total no. of mice)
SV5610/10
12610/10
5189/9
EV76569/9
12610/10
51810/10
Alum adjuvanted (control)560/10
1260/10
5180/10
  • a The challenge dose used for all treatment groups was 106 CFU of Y. pestis strain 141.