TABLE 2.

Experimental design for testing protective efficacy of WN-80E vaccine in rhesus monkeysa

GroupNo. of animalsWN-80E dose (μg)Adjuvant dose (mg)
1552
2402
  • a Four doses of vaccine were administered, on days 0, 21, 42, and 230. Animals were challenged on day 290. One animal from group 1 was euthanized after completion of the vaccination schedule but prior to challenge due to chronic severe anemia of an unknown origin that was nonresponsive to nutritional supplementation, as well as abnormal behaviors.