TABLE 2.

B-cell and CD4-cell activation and proliferation in response to various stimulia

ComparisonP valueb
B-cell activationB-cell proliferationT-cell activationT-cell proliferation
α-δ-Dex stimulation vs unstimulated group0.00010.0001NSNS
CD3NDND0.00230.0002
CD3/CD28 vs unstimulated group0.00010.00020.00020.0001
CD3/CD28 vs CD3NDND0.01070.0001
CD3/CD28/α-δ-dex vs CD3/CD280.00010.0001NDND
  • a Combinations of control and patient samples are shown for simplicity. Both patient and control cells responded to all stimuli. All comparisons were done by the Wilcoxon signed rank test for nonparametric paired data.

  • b ND, not determined; NS, not significant.