TABLE 5.

Detection of anthrax PA in mice infected with B. anthracis spores by ENIAa

Dosage (no. of spores/mouse)Bleed time (h)No. of animalsIllness gradePA concn in blood (ng/ml)
10324-237130.00
107620.00
107820.00
107242+b68 ± 75
10742-482+++408 ± 275
02420.00
  • a DBA/2J mice were exposed to different doses of B. anthracis spores and were bled at different times after infection. PA levels in plasma were assessed by ENIA. The samples were diluted from 1:10 to 1:1,000.

  • b Edema.