TABLE 1.

Total pathology scores and antibody responses to M. bovis antigens as measured by MAPIA and RT densitometry in vaccinated and nonvaccinated deer after M. bovis challengea

Vaccination group and animal identifierRelative antibody density over that at the baseline determined by:Total pathology score (avg)
MAPIART
E6P1016/83MBCF
Oral bait
    4020041b,c00
    404015b0c00
    4060c0c5b,c00
    4100c0c0c02
    4180c0c13c01
        Totald0/51/53/50/53 (0.6)
Oral liquid
    1400000
    2038b0000
    8100000
    8400001
    41600000
        Total1/50/50/50/51 (0.2)
Parenteral
    100c0b,c87b0
    230c0c63b,c00
    260c0c0b,c01
    590c083b00
    730c16c003
    9100000
        Total0/61/62/61/64 (0.7)
Nonvaccinated animals
    39416963216
    1910c3c45c,e205
    221228963911
    240c0c0c,e05
    5700902719
    422045859030
        Total3/64/65/65/686 (14)
  • a Measurements were made 4 months after intratonsillar infection with 228 CFU of M. bovis for E6P10, 16/83, and RT and at 2 months postinfection for MBCF.

  • b The antibody titer was over that at the baseline 1 to 3 months postvaccination, prior to M. bovis challenge.

  • c Antibody was detected in the baseline sample.

  • d Number of animals with antibodies/total number of animals tested.

  • e Antibody was detected in unvaccinated animals 1 to 3 months prior to M. bovis challenge.