TABLE 1.

Characteristics of experimentally infected armadillos

ArmadilloIdentifierM. leprae burden at end of exptProtein(s) that elicited earliest response(s)aEarliest time of response (mo)Protein(s) that elicited largest response(s)b
Liver (109/g)Spleen (1010/g)
18A252.431.60NDO-BSA,c ML234614, 29ML2346
21X1.156.60ML04119PADL
32X0.510.47NDO-BSAc,d12NDO-BSAd
46R361.040.59NDO-BSAc,d5PADL
57M441.720.22LID-1, NDO-BSA,c,d ML0411, PADL, ML234611PADL
66I631.100.41LID-1, NDO-BSA,c,d ML041111LID-1, PADL
76H491.761.74NDO-BSAc,d3PADL
86G231.796.26LID-1, NDO-BSAc6LID-1, PADL
95B335.532.93NDO-BSAc,d3PADL
108A800.650.03NDO-BSAd2PADL
  • a Responses against recombinant proteins or NDO-BSA detected with protein A were considered positive when a value greater than 3 times the preinoculation levels was detected. Anti-NDO-BSA responses detected with anti-IgM antibodies were considered positive when values of >700 units were attained.

  • b The largest response was determined as the highest OD value regardless of time.

  • c Detected with anti-IgM antibodies.

  • d Detected with protein A.