TABLE 2.

Serotyping results for samples from patients with infections due to archetypal strains (type I, II, or III)a

Case no.PathologyGeographical originOD index for:bGRA6 serotypecGRA6 C-terminal polymorphismdGenotype
GRA6 IIGRA6 I/III
1CongenitalFrance0.054−0.029NDGSEFII
2CongenitalFrance0.269−0.019IIGSEFII
3CongenitalFrance0.2130.011IIGSEFII
4CongenitalFrance0.302−0.025IIGSEFII
5CongenitalFrance0.0710.023NDGSEFII
6CongenitalFrance0.096−0.011IIGSEFII
7CongenitalFrance0.432−0.044IIGSEFII
8CongenitalFrance0.3300.023IIGSEFII
9CongenitalFrance2.088−0.004IIGSEFII
10CongenitalFrance0.217−0.018IIGSEFII
11CongenitalFrance0.1100.002IIGSEFII
12CongenitalFrance0.298−0.032IIGSEFII
13CongenitalFrance0.279−0.029IIGSEFII
14CongenitalFrance0.195−0.025IIGSEFII
15CongenitalFrance0.183−0.034IIGSEFII
16CongenitalFrance0.150−0.007IIGSEFII
17CongenitalFrance0.2180IIGSEFII
18CongenitalFrance0.159−0.007IIGSEFII
19CongenitalFrance−0.0310.123I/IIIERVYIII
20CongenitalFrance0.0110.118I/IIIERVYIII
21CongenitalFrance0.0080.312I/IIIERVYIII
22LymphadenopathyFrance0.0811.149I/IIIERVYI
23DisseminatedFrance0.0050.020NDGSEFII
  • a For congenital infections, the OD indices presented were obtained for serum samples from newborns, except for cases number 6, 8, and 10 obtained from mothers.

  • b OD indices were calculated by subtracting the OD of the peptide control from the OD of each peptide. The cutoff values for European samples were 0.088 for GRA6 II and 0.076 for GRA6 I/III.

  • c ND, not determined because the serum sample had an OD index that was below the cutoff value.

  • d The amino acid polymorphisms from the C-terminal region of GRA6 are at positions 223, 224, 227, and 230.