TABLE 5.

IFN-γ responses of children aged 6 to <36 months to influenza virus following vaccination

VaccineA/H1N1A/H3N2B
Day 6Day 13Day 6Day 13Day 6Day 13
naMFRb (95% CI)nMFR (95% CI)nMFR (95% CI)nMFR (95% CI)nMFR (95% CI)nMFR (95% CI)
CAIV-T 10787.15 (1.00, 303.0)555.0 (37.0, 227.0)71.00 (1.00, 30.0)436.5 (3.94, 193.0)63.00 (1.00, 20.0)473.5 (1.00, 237.0)
CAIV-T <10571.00 (1.00, 1.18)101.00 (1.00, 1.00)71.00 (0.67, 1.00)71.00 (1.00, 1.00)31.00 (1.00, 10.0)41.00 (1.00, 7.00)
TIV71.00 (1.00, 29.0)93.00 (1.00, 5.67)62.00 (1.00, 3.00)62.50 (1.00, 41.3)21.00 (1.00, 1.00)21.00 (1.00, 1.00)
Placebo61.00 (1.00, 1.00)61.00 (0.50, 1.00)61.00 (1.00, 1.00)41.00 (1.00, 1.00)31.00 (0.08, 1.00)31.00 (1.00, 1.00)
  • a Number of subjects in the analysis. This number was largely dependent on the number of subjects with sufficient blood volume drawn to enable the conduct of the assay.

  • b MFR, median fold rise in the postvaccination compared with the prevaccination sample.