TABLE 4.

Results of LFD tests of serum samples from healthy individuals or from patients with known or suspected IA

Specimen no.IAaPlatelia GM EIA index valuePlatelia GM EIA resultFungitell test β-glucan concn (pg/ml)Fungitell test resultLFD resultb
6OHDNo45.90Negative
7OHDNo42.40Negative
8OHDNo44.30Negative
9OHDNo44.09Negative
813Yes0.12Negative128.35Positive
815Yes0.36Negative360.49Positive
1263Yes0.16Negative111.72Positive
1652Yes0.32Negative111.94Positive
1655Yes0.35Negative104.13Positive+c
1657Yes0.71Positive122.23Positive±
1665Yes0.16Negative108.28Positive±
1667Yes0.30Negative142.19Positive±
1130Probable2.04Positive85.51Equivocal+
1131Probable1.52Positive219.61Positive+
1537Probable4.64Positive782.95Positive+c
1538Probable4.64Positive>500Positive+c
  • a Proven or probable cases of disease formally classified according to EORTC criteria.

  • b Reactions in LFD tests: −, no antigen detected; ±, weak reaction; +, strong reaction. The results for specimens 9OHD, 1657, and 1131 are shown in Fig. 4.

  • c Samples with a strong reaction at a 1 in 10 dilution in normal serum but negative undiluted.