TABLE 1.

Effect of Cy and RB6-8C5 treatments on white blood cell counts in BALB/c mice

Exptl groupCell count (103 cells/μl)a
WBCNELY
Cy,b day 19.411 ± 3.6151.009 ± 0.61917.741 ± 2.866
Saline, day 112.33 ± 0.70751.246 ± 0.276810.13 ± 0.7358
Cy, day 33.66 ± 1.2280.686 ± 0.41212.631 ± 0.7553
Saline, day 37.132 ± 3.4540.7100 ± 0.71245.976 ± 2.578
Cy, day 61.417 ± 0.51770.2256 ± 0.18391.059 ± 0.3115
Saline, day 611.85 ± 1.9941.809 ± 0.40629.239 ± 1.448
RB6-8C5,c day 1NDd0.1821 ± 0.38652.504 ± 0.9555
PBS, day 1ND0.9100 ± 0.15775.998 ± 1.483
  • a Total white blood cell (WBC), neutrophil (NE), and lymphocyte (LY) counts as determined using a Hemavet 850. Values are means ± standard errors.

  • b Cy (150 mg/kg) was given on days 1, 3, and 5, and blood was drawn on days 1, 3, and 6 for quantification of WBC.

  • c RB6-8C5 antibody was given i.p. to mice (2.0 mg) 1 day before the blood was drawn for quantification.

  • d ND, not determined.