TABLE 2.

Performance of the first p24 assay on DBS from 6-week-old infants and from children between 6 weeks and 6 years of age

Assay material6-wk-old infantsChildren >6 wk and <6 yr
No. of childrenPositive predictive value (%)dNegative predictive value (%)dNo. of childrenPositive predictive value (%)dNegative predictive value (%)d
TotalWith false-positive resultsWith false-negative resultsTotalWith false-positive resultsWith false-negative results
Grade 1 paper
    Without desiccant7501a100 (64.6, 100)98.6 (92.2, 99.7)4901c100 (92.7, 100)0 (0, 79.3)
    With desiccant7200100 (64.6, 100)100 (94.4, 100)4902a,c100 (92.7, 100)0 (0, 65.8)
903 card
    Without desiccant7502a,b100 (64.6, 100)97.1 (90.2, 99.2)5000100 (92.9, 100)
    With desiccant7200100 (64.6, 100)100 (94.4, 100)4901a100 (92.7, 100)0 (0, 79.3)
  • a False-negative p24 result on DBS on both filter paper types from the same child.

  • b False-negative result on DBS on 903 card but not on grade 1 paper from the same child.

  • c False-negative result on DBS on grade 1 paper but not on 903 card from the same child.

  • d Values in parentheses are 95% confidence intervals.