TABLE 4.

Concordance and agreement (Cohen's κ coefficient) between TST, T-SPOT.TB, and QFN-G-IT results for different groups of patients

Patient groupTST vs T-SPOT.TBTST vs QFN-G-ITT-SPOT.TB vs QFN-G-IT
Concordancea (%)κ (SE)Concordancea (%)κ (SE)Concordancea (%)κ (SE)
Patients with active TB36/42 (85.7)0.30 (0.237)34/42 (81)0.28 (0.159)34/40 (85)0.49 (0.173)
Contact tracing study
    Non-BCG-vaccinated subjects110/142 (77.5)0.58 (0.066)100/142 (70.4)0.44 (0.066)120/142 (84.5)0.71 (0.050)
    BCG-vaccinated subjects67/128 (52.3)0.14 (0.046)51/128 (39.8)0.06 (0.036)98/128 (76.6)0.52 (0.073)
    Overall177/270 (65.6)0.35 (0.046)151/270 (55.9)0.29 (0.040)218/270 (80.7)0.61 (0.047)
Screening for LTBI
    Non-BCG-vaccinated subjects127/178 (71.3)0.47 (0.055)118/178 (66.3)0.39 (0.053)153/178 (86)0.72 (0.054)
    BCG-vaccinated subjects64/136 (47.1)0.12 (0.042)61/136 (44.9)0.11 (0.040)117/136 (86)0.69 (0.065)
    Overall191/314 (60.8)0.30 (0.037)179/314 (57)0.25 (0.035)270/314 (86)0.71 (0.041)
  • a No. of patients with concordant results/total no. of patients.