TABLE 2.

OPA titer of absorbed and nonabsorbed IG to Pnc serotypes 15B and 15Ca

Target bacterium for OPAMedian OPA titer
IG absorbed with live bacteriabIG absorbed with Psc
NonabsorbedPnc 15B (DS4304-03)Pnc 15C (DS1615-95)NonabsorbedPnc 15B-Ps (native)Pnc 15B-Ps (de-O acetylated)
15B DS4304-031284d1281288e64
15C DS1615-9532644641288
  • a Experiments were performed in duplicate on two to three separate assay days.

  • b The strain designation is in parentheses.

  • c Pnc serotype 15B PS (native or deacetylated) concentration, 5 mg/ml.

  • d An OPA titer of <8 was reported as a titer of 4.

  • e An OPA titer of <16 was reported as a titer of 8. A dilution of 1:16 was the lowest dilution that could be tested under the assay conditions.