TABLE 3.

Animal-to-animal variation of antibody recognition of the two immunodominant antigens during experimental TB in rhesus macaques evaluated at the TNPRC and the University of South Alabama

M. tuberculosis strain (dose [CFU]) and animal identification no.Antibody responsea
ESAT-6MPB83
Erdman (30)
    209++
    283+++
    304++
    653
    814+++
Erdman (100)
    847++
    855++
    861+
    867+
    056+
H37Rv (210)
    590+
    595+++
    727++
    729++++++
  • a The results for antigens eliciting the earliest antibody in each infected animal are in bold. The magnitude of the antibody response was visually scored for each antigen as very strong (+++), strong (++), weak (+), or nonreactive (−).