TABLE 3.

Animal-to-animal variation of antibody recognition of the two immunodominant antigens during experimental TB in rhesus macaques evaluated at the TNPRC and the University of South Alabama

M. tuberculosis strain (dose [CFU]) and animal identification no.Antibody responsea
ESAT-6MPB83
Erdman (30)
    209 ++
    283 ++ +
    304+ +
    653
    814+ ++
Erdman (100)
    847+ +
    855 + +
    861 +
    867+
    056 +
H37Rv (210)
    590 +
    595 +++
    727+ +
    729 +++ +++
  • a The results for antigens eliciting the earliest antibody in each infected animal are in bold. The magnitude of the antibody response was visually scored for each antigen as very strong (+++), strong (++), weak (+), or nonreactive (−).