TABLE 1.

Analysis of the CDR and human subgroup assignments for the three anti-PvRII scFvs in this studya

Clone and regionSequence for:Family
CDR1CDR2CDR3
VL
    SFDBII12GFTFGDYAMETHGISWNSGSIGGMETAANYYYYYGMETDVVκIII
    SFDBII58GFTFGDYGMETHGISWNSGSIGDIYSSSWYAAFDIVκI
    SFDBII92GFTFSSYWMETSNIKQDGSEKYDCSSTSCYGYYYGMETDVVλI
VH
    SFDBII12RASQSVSSSYLAGASSRATQQYGSSRLTVHIII
    SFDBII58RASQSISYHLNAASTLQSQKYNSAPLTVHIII
    SFDBII92SGSSSNIGSNTVNSNNQRPSAAWDDSLNGWVVHIII